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''Hortaea werneckii'' is a species of yeast in the family Teratosphaeriaceae.〔http://www.doctorfungus.org/thefungi/hortaea.htm〕 It is a black yeast that is investigated for its remarkable halotolerance. While the addition of salt to the medium is not required for its cultivation, ''H. werneckii'' can grow in close to saturated NaCl solutions. To emphasize this unusually wide adaptability, and to distinguish'' H. werneckii'' from other halotolerant fungi, which have lower maximum salinity limits, some authors describe ''H. werneckii'' as "extremely halotolerant".〔 Several salt-tolerance mechanisms of ''H. werneckii ''have been studied on molecular level.〔 For example it is known that its major compatible solutes are glycerol, erythritol, arabitol, and mannitol; melanin accumulation of the cell wall aids in retention of at least glycerol inside of the cell.〔 Several components of the high osmolarity glycerol (HOG) signalling pathway (which controls responses to osmotic shock) have been studied in detail and some seem to differ in function compared to their counterparts in ''Saccharomyces cerevisiae''. Adaptation to high concentrations of salt are also accompanied by changes in membrane lipid composition, mainly by increasing the unsaturation of the phospholipid fatty acids. ''H. werneckii ''causes a rare superficial and non-invasive skin infection Tinea nigra. The typical symptoms are non-scaly, smooth, brown-black painless spots on the palms of hands and soles of feet. The growth of ''H. werneckii'' in liquid media is often yeast-like, although it can switch to filamentous growth. The mechanism of the switch is not known. The cells appear brown because of melanin production.〔 Whole genome sequencing of ''H. werneckii'' revealed a recent whole genome duplication, resulting in a relatively large genome (51.6 Mb) with 23333 predicted genes. Genes encoding metal cation transporters, which are thought to play a role in halotolerance, experienced several additional gene duplications at various points during their evolution. A heterothallic mating locus was found in the genome. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Hortaea werneckii」の詳細全文を読む スポンサード リンク
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